JAMES (Robert) DIDEROT (Denis). Dictionnaire universel de médecine, de chirurgie, de chymie, de botanique, d'anatomie, de pharmacie, d'histoire naturelle c. Paris, Briasson, David, Durand, 1746-1748. 6 volumes in-folio. First French edition translated by Diderot, Eidous and Toussaint and largely enlarged by Julien Busson, complete with its 68 folding plates bound at the end of the volumes. Bound in full tan calf, the boards embossed with a large frame of foliage scrolls, spine with six richly decorated bands. (Worn bindings, cracked bindings, missing headpieces, epidermis, folds on some plates and tiny freckles and stains)